Program DHC-Virtual

20 - 21 January 2021

 

 

Wednesday 20 January
Virtual room 1
08:25 - 08:30
Opening
Virtual room 2
08:25 - 08:30
Opening
Virtual room 3
08:25 - 08:30
Opening
Virtual room 1
08:30 - 09:30
Clinical Abstracts session 1
Moderators:
Dr. H.J. Boiten,
Drs. T.T. de Waal
08:30 - 08:42
Long-term follow-up and biomarker analyses of r/r Hodgkin lymphoma treated with BV-DHAP.
Speaker:
J. Driessen
08:42 - 08:54
Effective treatment with Ibrutinib in cold agglutinin disease/cold agglutinin syndrome
Speaker:
M. Jalink
08:54 - 09:06
Predictive value of baseline radiomics features in DLBCL
Speaker:
J.J. Eertink
09:06 - 09:18
Impact of rituximab biosimilars on overall survival in DLBCL
Speaker:
M. Brink
09:18 - 09:30
Questions, answers and discussion
Virtual room 2
08:30 - 09:30
Abstracts Myeloid session 1
Moderators:
Dr. M. Corsten,
Dr. E.M. de Pater
08:30 - 08:42
Monocytosis and clonal hematopoiesis in older individuals
Speaker:
I. van Zeventer
08:42 - 08:54
The role of P-selectin in hematopoietic stem cell aging
Speaker:
D. Yang
08:54 - 09:06
LSD1/KDM1A and GFI1B orchestrate hematopoietic emergence from iPSC
Speaker:
H. Zhang
09:06 - 09:18
Untargeted Metabolomics in Rare Hereditary Anemia
Speaker:
B. van Dooijeweert
09:18 - 09:30
Questions, answers and discussion
Virtual room 3
08:30 - 09:30
Abstracts Lymphoid session I
Moderators:
Dr. F.S. Kleijwegt,
Dr. R. Mous
08:30 - 08:42
Oncogenic and Metabolic Features of AKT/FOXO signaling in Multiple Myeloma
Speaker:
T.A. Bloedjes
08:42 - 08:54
Rosetting T cells in Hodgkin lymphoma
Speaker:
J. Veldman
08:54 - 09:06
Towards predicting response to daratumumab therapy in relapsed/refractory multiple myeloma
Speaker:
N. van Nieuwenhuijzen
09:06 - 09:18
Mutational analysis in relapsed DLBCL
Speaker:
M. Berendsen
09:18 - 09:30
Questions, answers and discussion
1. virtual room
09:30 - 10:00
Coffee/tea break
Virtual room 1
10:00 - 11:00
Clinical Abstracts session 2
Moderators:
Dr. D. Evers,
Dr. B. Moens
10:00 - 10:12
Atypical presentation of VWD leading to discovery of novel VWF mutation
Speaker:
T. van de Berg
10:12 - 10:24
Treatment of patients with rare bleeding disorders in the Netherlands
Speaker:
D. Maas
10:24 - 10:36
Aplastic Anaemia in the Netherlands
Speaker:
L. Bogers
10:36 - 10:48
Implementation of a standardised Palliative Care Pathway
Speaker:
A. van der Padt Pruijsten
10:48 - 11:00
Questions, answers and discussion
Virtual room 2
10:00 - 11:00
Abstracts Myeloid session 2
Moderators:
Dr. E. van den Akker,
Dr. C.M. Woolthuis
10:00 - 10:12
Leukemic stem cells in MDS/AML by CyTOF
Speaker:
C. Bachas
10:12 - 10:24
Mutant p53 in leukemic cells
Speaker:
M. Gerritsen
10:24 - 10:36
Is there a role for nuclear DNA sensors in anthracycline induced cell death?
Speaker:
S. van der Zanden
10:36 - 10:48
GATA2 allele-specific expression in CEBPA DM AML
Speaker:
R. Mulet-Lazaro
10:48 - 11:00
Questions, answers and discussion
Virtual room 3
10:00 - 11:00
Abstracts Immunology session 1
Moderators:
Dr. J. van Elssen,
Dr. M. Themeli
10:00 - 10:12
TCR-targeting of immunoglobulins for multiple myeloma
Speaker:
M.H. Meeuwsen
10:12 - 10:24
Preclinical activity of talquetamab in multiple myeloma
Speaker:
C. Verkleij
10:24 - 10:36
Split signaling CAR T cells to treat multiple myeloma
Speaker:
J. van der Schans
10:36 - 10:48
Inhibition of MICA and MICB shedding in Multiple Myeloma
Speaker:
S. Tahri
10:48 - 11:00
Questions, answers and discussiom
1. virtual room
11:00 - 11:30
Coffee/tea break
Virtual room 1
11:30 - 12:30
Clinical Abstracts session 3
Moderators:
Dr. P. von dem Borne,
Dr. E.M.P. Cremers
11:30 - 11:42
HOVON143: Ixa-Dara-dex in intermediate fit and frail multiple myeloma patients
Speaker:
C. Stege
11:42 - 11:54
Revised frailty assessment in elderly myeloma patients
Speaker:
C. Stege
11:54 - 12:06
Primary therapy and relative survival in patients with lymphoplasmacytic lymphoma/Waldenst
Speaker:
K. Amaador
12:06 - 12:18
Early mortality in multiple myeloma
Speaker:
M. Brink
12:18 - 12:30
Questions, answers and discussiom
Virtual room 2
11:30 - 12:30
Abstracts Lymphoid session 2
Moderators:
Dr. J.L. Kluiver,
Drs. H. Masquillier
11:30 - 11:42
Primary bone DLBCL is characterized by GCB mutations with a favorable survival
Speaker:
R. de Groen
11:42 - 11:54
Identification of venetoclax-sensitizers in mantle cell lymphoma by a CRISPR screen
Speaker:
Y. Thus
11:54 - 12:06
Effects of Ibrutinib on Metabolic Alterations and Micro-environmental Signalling in CLL
Speaker:
Y. Chen
12:06 - 12:18
Reproducibility of gene expression signatures in diffuse large B-cell lymphoma
Speaker:
J. Rodrigues Placa
12:18 - 12:30
Questions, answers and discussion
Virtual room 3
11:30 - 12:30
Abstracts Immunology session 2
Moderators:
Dr. E. Bremer,
Dr. S. van Dorp
11:30 - 11:42
A novel Dual Signaling Protein that activates innate and adaptive anticancer immunity
Speaker:
E. Cendrowicz
11:42 - 11:54
HA-1H TCR gene transfer
Speaker:
P. van Balen
11:54 - 12:06
CD4 T cell immune reconstitution predicts survival after aGvHD
Speaker:
C. de Koning
12:06 - 12:18
The CCL4-CCR5 axis promotes local T-cell migration of cellular immunotherapy in leukemia
Speaker:
A. Meringa
12:18 - 12:30
Questions, answers and discussiom
1. virtual room
12:30 - 13:30
Lunch break
Virtual room 1
13:30 - 14:30
MPN, en dan.......?
Moderators:
Dr. S. Kersting,
Dr. P.A.W. te Boekhorst
13:30 - 13:50
MPN, Trombose & Antistolling
Speakers:
Drs. E.N. Hamulyák,
Dr. M.N. Lauw
13:50 - 14:10
Polyglobulie maar geen PV
Speaker:
Drs. A.E. Pulles
14:10 - 14:30
Myelofibrose & Anemie
Speakers:
Dr. M.W.H. Roeven,
Drs. T. J. Wustman
1. virtual room
14:30 - 15:00
Coffee/tea break
Virtual room 1
15:00 - 16:00
DHC Educational Indolent Lymfoom
Moderators:
Drs. E. de Jongh,
Dr. W.B.C. Stevens
15:00 - 15:15
Folliculair Lymfoom richtlijn: What's new?
Speaker:
Dr. S.H. Tonino
15:15 - 15:40
Nieuwe Marginale Zone Lymfoom richtlijn aan de hand van casuïstiek deel 1
Speakers:
Dr. H. Boot (MDL arts n.p.),
Dr. M Jak
15:40 - 16:00
Casuistiek deel 2
Speakers:
Dr. F. Ong,
Dr. C. Siemes
1. virtual room
16:00 - 16:30
Coffee/tea break
Virtual room 1
16:30 - 17:30
Tips & Tricks: Bijwerkingen nieuwe middelen MM
Moderators:
Prof. dr. P. Sonneveld,
Prof. dr. S. Zweegman


Commentaar: Prof. dr. N. van de Donk

16:30 - 16:40
De behandeling van MM- de kwaliteit betreft niet alleen respons
Speaker:
Prof. dr. S. Zweegman
16:40 - 17:10
Casus 1: Niet bekend maakt niet bemind- fine tuning van anti MM therapie
Speaker:
Drs. P. Ypma
17:10 - 17:30
Casus 2: Immuuntherapie - sexy, sensationeel, maar soms ook spannend
Speaker:
Drs. K. Groen
1. virtual room
17:30 - 18:00
De grote DHC Quiz: Daan Castelijn en Pauline de Jong
Virtual room 1
08:25 - 08:30
Opening
Virtual room 2
08:25 - 08:30
Opening
Virtual room 3
08:25 - 08:30
Opening
Virtual room 1
08:30 - 09:30
Abstracts Myeloid session 3
Moderators:
Dr. M. Nethe,
Dr. C. Voermans
08:30 - 08:42
The landscape of macrophages in AML
Speaker:
I. Weinhauser
08:42 - 08:54
Lipid Nanoparticles for siRNA delivery in t(8;21) AML
Speaker:
L. Swart
08:54 - 09:06
T cell receptor gene therapy for mutant NPM1
Speaker:
G. Koutsoumpli
09:06 - 09:18
Enhancer targeting in 3q26 rearranged AML
Speaker:
L. Smeenk
09:18 - 09:30
Questions, answers and discussion
Virtual room 2
08:30 - 09:30
Abstracts Lymphoid session 3
Moderators:
Prof. dr. E. Eldering,
Dr. T. van Meerten
08:30 - 08:42
Early detection of Chronic Lymphocytic Leukemia up to 18 years before diagnosis
Speaker:
M. Kolijn
08:42 - 08:54
Mutational mechanisms in childhood acute lymphoblastic leukemia with multiple relapses
Speaker:
S. Lelieveld
08:54 - 09:06
IRF8 is a transcriptional regulator of CD37 in DLBCL
Speaker:
A. van Spriel
09:06 - 09:18
Serpin B9 expression in malignant cells confers resistance to Granzyme B-mediated killing
Speaker:
T. Kimman
09:18 - 09:30
Questions, answers and discussion
Virtual room 3
08:30 - 09:30
Abstracts Immunology session 3
Moderators:
Dr. R. van Bruggen,
E. Dovern, MSc
08:30 - 08:42
Survival of transfused red blood cells in Sickle cell and β-Thalassemia patients
Speaker:
N. van der Bolt
08:42 - 08:54
Dissecting the pathophysiology of TRALI: focus on the pulmonary endothelium
Speaker:
E. Zeeuw van der Laan
08:54 - 09:06
VISTA expression associates with survival in multiple myeloma
Speaker:
P. Mutsaers
09:06 - 09:18
Myeloid progenitors as cells of origin in Langerhans cell histiocytosis
Speaker:
Y. Xiao
09:18 - 09:30
Questions, answers and discussion
1. virtual room
09:30 - 10:00
Coffee/tea break
Virtual room 1
10:00 - 11:00
Abstracts Myeloid session 4
Moderators:
Dr. V. van den Boom,
Dr. C. Voermans
10:00 - 10:12
E-cadherin controls erythropoiesis; a novel avenue to treat anaemia
Speaker:
R. Krimpenfort
10:12 - 10:24
Characterization of a locus downstream of GFI1B associated with MPN
Speaker:
M. van Bergen
10:24 - 10:36
Mutational consequences of hematopoietic stem cell transplantation in humans
Speaker:
F. Peci
10:36 - 10:48
Targeting histone methylation to overrule transcriptionally driven drug resistance
Speaker:
N. van Gils
10:48 - 11:00
Questions, answers and discussion
Virtual room 2
10:00 - 11:00
Abstracts Benigne
Moderators:
Prof. dr. R.E.G. Schutgens,
Dr. G.A. Velders
10:00 - 10:12
Comparison of FVIII activity (OSA) and concentration (MS) in haemophilia A patients
Speaker:
A. Donners
10:12 - 10:24
Genome editing in CD34 cells to cure sickle cell disease and thalassemia
Speaker:
H. Verhagen
10:24 - 10:36
Hemolysis in the spleen drives erythrocyte turnover
Speaker:
T. Klei
10:36 - 10:48
TSAT/Hepcidin ratio discriminates TMPRSS6-related IRIDA from IDA
Speaker:
H. van der Staaij
10:48 - 11:00
Questions, answers and discussion
Virtual room 3
10:00 - 11:00
Abstracts Immunology session 4
Moderators:
Dr. S. Klobuch,
M. Plantinga, PhD
10:00 - 10:12
CD34+-derived DC subsets exhibit subset-specific features and boost anti-tumor immunity
Speaker:
J. van Eck van der Sluijs
10:12 - 10:24
High-dimensional immune profiling and unsupervised clustering analyses in MDS patients
Speaker:
D. van Ens
10:24 - 10:36
Leukemia-induced T cell dysfunction reveals mitochondrial defects in an in vitro model
Speaker:
C. Montironi
10:36 - 10:48
Skewing of the antigen-specific T cell response in CLL
Speaker:
F. Peters
10:48 - 11:00
Questions, answers and discussion
1. virtual room
11:00 - 11:30
Coffee/tea break
Virtual room 1
11:30 - 12:30
Clinical Abstracts session 4
Moderators:
Dr. L van Hussen - Daenen,
Dr. L. Nieuwenhuizen
11:30 - 11:42
Short versus extented treatment with a carbapenem for high risk fever during neuropenia
Speaker:
N. de Jonge
11:42 - 11:54
Conditional relative survival among long-term AML survivors
Speaker:
A. Dinmohamed
11:54 - 12:06
Two decades of targeted therapies in acute myeloid leukemia
Speaker:
D.G.J. Cucchi
12:06 - 12:18
HLA class I alloimmunization among hematological patients
Speaker:
R. Wijgers
12:18 - 12:30
Questions, answers and discussion
Virtual room 2
11:30 - 12:30
Abstracts Lymphoid session 4
Moderators:
Dr. A. Diepstra,
Dr. J.E.J. Guikema
11:30 - 11:42
Outcome of ABL-class ALL in children in the pre-tyrosine kinase inhibitor era
Speaker:
J. Boer
11:42 - 11:54
(Sub)clonal architecture and temporal dynamics of the TCR repertoire in T-LGL leukemia
Speaker:
J. Assmann
11:54 - 12:06
A roadmap for human T cell development
Speaker:
K. Cante Barrett
12:06 - 12:18
Non-Hodgkin lymphoma after classic Hodgkin lymphoma, consequences of Hodgkin mimickers
Speaker:
M. Boot
12:18 - 12:30
Questions, answers and discussion
1. virtual room
12:30 - 13:30
Lunch break
Virtual room 1
13:30 - 14:30
Veilig chemotherapie toedienen bij de mensen thuis, ervaringen en uitdagingen in de praktijk
Moderators:
Dr. E.J.F.M. de Kruijf,
Dr. M.A. de Witte
13:30 - 14:00
Wie dient het toe? Wie garandeert de veiligheid? Wie betaalt het?
Speakers:
Dr. R. Boersma,
K. Dikkema de Jong,
Y. Heijmans,
Dr. J. van den Heuvel
14:00 - 14:30
Discussie en vragen
1. virtual room
14:30 - 15:00
Coffee/tea break
Virtual room 1
15:00 - 16:00
DHC Educational: Thrombocytentransfusies
Moderators:
Prof. dr. E.A.M. Beckers,
Prof. dr. J.J. Zwaginga
15:00 - 15:30
Thrombocyten profylaxe: pathofysiologie en risico factoren bloedingen
Speaker:
Drs.L. Cornelissen
15:30 - 16:00
Thrombocyten profylaxe in de dagelijkse praktijk
Speaker:
Drs. C.S Ootjers
Virtual room 1
16:00 - 16:15
Uitreiking Steenbergen Stipendium
Speaker:
Prof. dr. F.W.G. Leebeek
16:00 - 16:15
Presentatie winnaar Steenbergen Stipendium
1. virtual room
16:15 - 16:30
Coffee/tea break
Virtual room 1
16:30 - 17:30
Covid 19: Uitdagingen binnen de hematologie
Moderators:
Prof. dr. K. Meijer,
Dr. E. Nur
16:30 - 17:00
Covid-19 pathogenese en behandeling: waar staan we?
Speaker:
Prof. dr. W.J. Wiersinga
17:00 - 17:30
Covid-19 : een bloedstollende wending
Speaker:
Dr. K. Winckers
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